Oral Communications (OC)

OC1
EFFICACY AND SAFETY OF ROMOSOZUMAB AMONG POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS AND MILD-TO-MODERATE CHRONIC KIDNEY DISEASE
D. Miller, J. Adachi, B.-H. Albergaria, A. M. Cheung, A. Chines, E. Gielen, B. Langdahl, A. Miyauchi, M. Oates, I. R. Reid, N. Ruiz Santiago, M. Vanderkelen, W. Yang, Z. Yu

OC2
ROMOSOZUMAB AFTER DENOSUMAB IMPROVES LUMBAR SPINE AND MAINTAINS TOTAL HIP BONE MINERAL DENSITY IN POSTMENOPAUSAL WOMEN WITH LOW BONE MASS
M. R. McClung , M. A. Bolognese , J. P. Brown , J.-Y. Reginster , B. L. Langdahl , N. Ruiz-Santiago , Y. Shi , M. Rojeski , J. Timoshanko , C. Libanati , H. Kassahun , M. Oates

OC3
VERTEBRAL FRACTURES BEFORE, DURING AND AFTER DENOSUMAB. A RETROSPECTIVE STUDY OF 858 CASES
P. Burckhardt, O. Lamy, T. H. Buclin, M. Faouzi, D. Aeberli, F. Cattaneo, J. Dudler, M. Felder, D. Frey, P. Hasler, H. J. Häuselmann, S. Jehle-Kunz, I. Krull, T. H. Lehmann, K. Lippuner, C. Meier, U. Moser, M. Oehri, A. Rohrer, F. Tanzi, M. Toniolo, B. Uebelhart, L. Wildi, D. Wildpaner

OC4
DIFFERENTIAL EFFECTS OF ABALOPARATIDE AND TERIPARATIDE ON CORTICAL VOLUMETRIC BMD AND BONE STRENGTH INDICES IN THE PROXIMAL FEMUR BY DXA-BASED 3D MODELING
R. Winzenrieth, S. Ominsky , Y. Wang , L. Humbert , J. Weiss

OC5
FRACTURE RISK REDUCTION BY ANTI-OSTEOPOROSIS PHARMACOTHERAPY ACCORDING TO BASELINE RISK FACTORS AMONG POSTMENOPAUSAL WOMEN: METAREGRESSION ANALYSES OF RANDOMISED TRIALS
M. N. Händel, I. Cardoso, C. Von Bülow, J. F. Rohde, A. Ussing, S. M. Nielsen, R. Christensen, B. Langdahl, T. Thomas, J.-J. Body, M. L. Brandi, A. Diez-Perez, P. Hadji, M. K. Javaid, W. F. Lems, X. Nogues, C. Roux, S. Minisola, A. Kurth, S. L. Ferrari, D. Prieto-Alhambra, B. Abrahamsen

OC6
BUROSUMAB IMPROVES BIOCHEMICAL, SKELETAL, AND CLINICAL FEATURES OF TUMOR-INDUCED OSTEOMALACIA (TIO) SYNDROME
S. Jan de Beur, P. D. Miller, T. J. Weber, M. Peacock, K. L. Insogna, R. Kumar, D. Luca, T. Cimms, M. S. Roberts, T. O. Carpenter

OC7
TEMPORAL TRENDS AND FACTORS ASSOCIATED WITH BISPHOSPHONATE DISCONTINUATION AND RESTART
G. Adami, A. Jaleel , J. C. Curtis , E. Delzell , R. Chen , H. Yun, S. Daigle, T. Arora, M. I. Danila, N. C. Wright, S. M. Cadarette, A. S. Mudano, J. Foster, K. G. Saag

OC8
MACROBIOTIC DIETS, PLANT-BASED DIETS, VEGETARIANISM, VEGANISM AND BONE HEALTH: A SYSTEMATIC REVIEW AND META-ANALYSES
I. Iguacel, L. A. Moreno

OC9
DISEASE PHENOTYPE AS A PREDICTOR OF TREATMENT RESPONSE IN OSTEOARTHRITIS: RESULTS FROM A PHASE II CLINICAL TRIAL OF THE FIRST-IN-CLASS IMIDAZOLINE-2 RECEPTOR LIGAND CR4056
L. C. Rovati, N. Brambilla, T. Blicharski, J. Connell, C. Vi- talini, A. Bonazzi, G. Giacovelli, F. Girolami, M. D’Amato

OC10
THE NOVEL, INTRA-ARTICULAR CLK/DYRK1A INHIBITOR LORECIVIVINT (SM04690), A WNT PATHWAY MODULATOR, IMPROVED RESPONDER OUTCOMES IN SUBJECTS WITH KNEE OSTEOARTHRITIS: A POST HOC ANALYSIS FROM A PHASE 2B TRIAL
J. Tambiah, S. Kennedy , C. Swearingen , Y. Yazici

OC11
EFFICACY AND SAFETY OF AN INTRA-ARTICULAR INJECTION OF JTA-004, A NOVEL ENHANCED PROTEIN SOLUTION, IN KNEE OSTEOARTHRITIS PAIN: A RANDOMISED, DOUBLE-BLIND CONTROLLED PHASE II/III STUDY
M. Bettonville, M. Léon, J. Margaux, D. Urbin-Choffray, E. Theunissen, T. Besse-Hammer, Y. Fortems, S. Verlin- den, O. Godeaux, A.-S. Delmarcelle, J.-F. Kaux

OC12
CONFIRMED AND SEVERE SARCOPENIA BY EWGSOP2 PREDICT 10-YEAR FRACTURE RISK INDEPENDENT OF FRAX, FALLS AND BMD IN THE OSTEOPOROTIC FRACTURES IN MEN (MROS) STUDY: A META-ANALYSIS
N. C. W. Harvey, E. Orwoll, T. Kwok, M. K. Karlsson, B. E. Rosengren, E. Ribom, J. Cauley, P. M. Cawthon, K. Ens- rud, E. Liu, A. Cruz-Jentoft, C. Cooper, J. A. Kanis, M. Lorentzon, C. Ohlsson, D. Mellström, H. Johansson, E. McCloskey

OC13
MUSCLE DENSITY, BUT NOT SIZE, CORRELATES WELL WITH MUSCLE PERFORMANCE
L. Wang, Y. Yin, G. Guglielmi, X. Cheng, G. M. Blake, K. Engelke

OC14
THE MULTIDIMENSIONAL PROGNOSTIC INDEX PREDICTS FALLS IN OLDER PEOPLE: AN 8-YEAR LONGITUDINAL COHORT STUDY OF THE OSTEOARTHRITIS INITIATIVE
N. Veronese, G. Siri, A. Cella, S. Maggi, E. Zigoura, M. Puntoni, L. Smith, C. Musacchio, A. Barone, C. Sabbà, F. Vallone, A. Pilotto

OC15
5-YEAR ADVERSE OUTCOMES OF SARCOPENIA DIAGNOSED ACCORDING TO SIX DIFFERENT DEFINITIONS
L. Lengelé, C. Beaudart , M. Locquet , J.-Y. Reginster, O. Bruyère

OC16
LEVEL AND CHANGE IN SARCOPENIA COMPONENTS PREDICT ADVERSE HEALTH OUTCOMES: FINDINGS FROM THE HEALTH, AGING AND BODY COMPOSITION STUDY
L. D. Westbury, H. E. Syddall, N. R. Fuggle, E. M. Den nison, J. A. Cauley, E. J. Shiroma, R. A. Fielding, A. B. Newman, C. Cooper

OC17
RELATIONSHIP BETWEEN OBESITY AND RISK OF MAJOR OSTEOPOROTIC FRACTURE IN POSTMENOPAUSAL WOMEN: TAKING FRAILTY INTO CONSIDERATION
G. Li, Z. Li, L. Thabane, J. Adachi

OC18
IDENTIFICATION OF THE MOST IMPORTANT FEATURES OF KNEE OSTEOARTHRITIS PROGRESSORS USING MACHINE LEARNING METHODS
A. Jamshidi, M. Leclercq, A. Labbe, J.-P. Pelletier, F. Abram, A. Droit, J. Martel-Pelletier

OC19
RESVERATROL BENEFITS BONE HEALTH IN POSTMENOPAUSAL WOMEN – OUTCOMES OF THE TWO-YEAR RESHAW TRIAL
R. Wong, J. J. Thaung Zaw, C. Xian, P. Howe

OC20
GEOGRAPHICAL ASSESSMENT OF BONE MINERAL DENSITY WITH RELUGOLIX COMBINATION THERAPY: RESULTS FROM THE PHASE 3 LIBERTY PROGRAM
M. McClung, A. Al-Hendy, R. Venturella, J. Li, L. Mcka- in, R. Wagman

OC21
VITAMIN D SUPPLEMENTATION IN PREGNANCY RESULTS IN GREATER OFFSPRING BONE MASS AT 4 YEARS: FINDINGS FROM THE MAVIDOS TRIAL
E. M. Curtis, R. J. Moon, S. D’Angelo, S. R. Crozier, N. J. Bishop, S. Gopal-Kothandapani, S. Kennedy, A. T. Papa- georghiou, R. Fraser, S. V. Gandhi, I. Schoenmakers, A. Prentice, H. M. Inskip, K. M. Godfrey, M. K. Javaid, R. Eastell, C. Cooper, N. C. Harvey

OC22
SUPERIOR EFFICACY OF CALCIFEDIOL SOFT GELATIN CAPSULES VS CHOLECALCIFEROL FOR THE MANAGEMENT OF VITAMIN D DEFICIENCY IN POSTMENOPAUSAL WOMEN: A TREATMENT TO BE CONSIDERED IN THERAPEUTIC GUIDELINES
M. L. Brandi, J. L. Pérez-Castrillón, A. Dueñas-Laita, G. Hernández-Herrero, N. Fernández-Hernando, L. Elgeza- bal

OC23
PERIOSTEAL EXPANSION DOES NOT COMPENSATE LOSS OF BONE STRENGTH CAUSED BY ENDOSTEAL RESORPTION WITH AGING: A LONGITUDINAL HR-PQCT STUDY WITH 3D-REGISTRATION FROM THE GERICO COHORT
E. Biver, B. van Rietbergen, T. Chevalley, S. Ferrari

OC24
MEASURES OF MUSCLE ADIPOSITY, BUT NOT MUSCLE CROSS-SECTIONAL AREA, PREDICT FRACTURES INDEPENDENT OF FRAX, FALLS AND BMD IN THE OSTEOPOROTIC FRACTURES IN MEN (MROS) STUDY
N. C. W. Harvey, E. Orwoll, J. Cauley, T. Kwok, M. K. Karlsson, B. E. Rosengren, E. Ribom, P. M. Cawthon, K. Ensrud, E. Liu, K. Ward, C. Cooper, J. A. Kanis, M. Lorentzon, C. Ohlsson, D. Mellström, H. Johansson, E. McCloskey

OC25
A NEW PREDICTION TOOL BASED ON ELECTRONIC MEDICAL RECORDS DATA TO ASSESS IMMINENT HIP FRACTURE RISK IN SECONDARY FRACTURE PREVENTION: A COHORT ANALYSIS INCLUDING OVER 700,000 PATIENTS FROM DENMARK, SPAIN AND THE UK
M. T. Pineda-Moncusí, S. Khalid, L. Elhussein, C. Dy- er-Smith, A. Moayyeri, M. Ernst, D. Martinez-Laguna, X. Nogués, C. Reyes, E. Toth, F. Lebon, C. Libanati, M. Javaid, C. Cooper, B. Abrahamsen, D. Prieto-Alhambra

OC26
THE POTENTIAL FOR OPPORTUNISTIC IDENTIFICATION OF VERTEBRAL FRACTURES IN PATIENTS UNDERGOING A CT SCAN AS PART OF DAILY CLINICAL PRACTICE: A DESCRIPTIVE STUDY USING REGISTRY DATA
M. K. Skjødt , J. Nicolaes , C. D. Smith , J. Banefelt , F. Lebon, C. Libanati, K. R. Olsen, C. Cooper, B. Abrahamsen

OC27
A CLINICAL TOOL FOR AUTOMATED PREDICTION OF HIP AND MAJOR OSTEOPOROTIC AT FIVE- AND ONE-YEARS FRACTURES USING ELECTRONIC MEDICAL RECORDS DATA: THE EPIC STUDY
D. Martinez-Laguna, C. Tebé, N. Pallarés, C. Car- bonell-Abella, C. Reyes, X. Nogués, A. Diez-Perez, D. Prieto-Alhambra

OC28
HIGH RISK OF HIP FRACTURE AND HIP FRACTURES SAVED IN THE SCOOP STUDY
E. McCloskey, N. Harvey, H. Johansson, C. Cooper, J. Kanis & The Scoop Study Team

OC29
BONE MICROARCHITECTURE OR AREAL BONE MINERAL DENSITY FOR DISCRIMINATION OF VERTEBRAL DEFORMITY IN OLDER ADULTS: A CROSS-SECTIONAL STUDY
C. Ma, F. Wu, F. Pan, L. Laslett, A. Shah, K. Squibb, R. Zebaze, T. Winzenberg, G. Jones

OC30
NO NEGATIVE ASSOCIATIONS, AND EVEN SOME POSITIVE ONES, BETWEEN BONE MASS, MICROSTRUCTURE AND STRENGTH, AND DIETARY ACID LOAD IN A PROSPECTIVE COHORT OF COMMUNITY-DWELLING WOMEN AND MEN
M. Papageorgiou, F. Merminod, T. Chevalley, B. Van Rietbergen, S. Ferrari, R. Rizzoli, E. Biver

OC31
FREQUENCY OF NORMAL DXA AND T-SCORE OSTEOPOROSIS IN POSTMENOPAUSAL WOMEN WITH FRACTURE: A REGISTRY-BASED COHORT STUDY
N. Binkley, S. N. Morin, P. Martineau, L. M. Lix, D. Hans, W. D. Leslie

OC32
THE RISK OF HIP AND NON-VERTEBRAL FRACTURES IN PARKINSON’S DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS
M. Schini, T. Vilaca, E. Poku, S. Harnan, A. Sutton, I. E. Allen, S. Cummings, R. Eastell

OC33
MUSCLE DENSITY IS BETTER THAN BONE DENSITY IN THE DISCRIMINATION OF INCIDENT HIP FRACTURE: A PROPENSITY SCORE MATCHING STUDY
L. Wang, Y. Yin, G. B. Blake, X. Cheng, K. Engelke

OC34
EFFICACY OF SYMPTOMATIC TREATMENTS FOR KNEE OA: A SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS WITH A 6-MONTH TIME-HORIZON
C. Beaudart , L. Lengelé , A. Geerinck , V. Leclercq , D.Sanchez Rodriguez , O. Bruyère , J.-Y. Reginster

OC35
OSTEOGENESIS IMPERFECTA: FRACTURE CHARACTERISTICS DURING PREGNANCY AND POST-PARTUM
E. Koumakis, A. Dellal, M. Debernardi, B. Cortet, F. Debiais, R. M. Javier, T. Thomas, N. Mehsen, M. Co- hen-Solal, E. Fontanges, M. Laroche, C. Marcelli, K. Briot, C. Roux, C. Cormier

OC36
TREATMENT INITIATION RATE POST HIP FRACTURE AS A KEY INDICATOR IN AN ORTHOPAEDIC FRACTURE LIAISON SERVICE.
J. Delisle, B. Benoit, G. Y. Laflamme, S. Leduc, H. Ngyuen, P. Ranger, J. Fernandes

OC37
PHYSICAL PERFORMANCE TRAJECTORIES AND MORTALITY AMONG NURSING HOME RESIDENTS: THE RESULTS OF THE SENIOR COHORT
A. Charles, J. Detilleux, F. Buckinx, J.-Y. Reginster, B. Gruslin, O. Bruyère

OC38
LIFESTYLE, ANTHROPOMETRY, AND BONE HEALTH ACROSS THREE GENERATIONS OF THE HERTFORDSHIRE COHORT STUDY
S. Carter, C. Parsons, M. O’Breasail, K. Ward, C. Cooper, N. Harvey, E. Dennison, M. Clynes

OC39
THE DIFFERENT DIAGNOSIS CRITERIA OF THE EWGSOP2 DEFINITION AND LONG-TERM CLINICAL OUTCOMES
C. Beaudart, M. Locquet, L. Lengelé, J.-Y. Reginster, O. Bruyère

OC40
COST-EFFECTIVENESS OF BINOSTO (BUFFERED SOLUBLE ALENDRONATE 70 MG) EFFERVESCENT TABLET FOR THE TREATMENT OF POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS IN ITALY
M. Hiligsmann , S. Maggi, G. Onder, L. Galluzzo, J.-Y. Reginster