OP1 - P906 LONG-TERM SAFETY IN ADULTS WITH X-LINKED HYPOPHOSPHATEMIA (XLH) TREATED WITH BUROSUMAB, A FULLY HUMAN MONOCLONAL ANTIBODY AGAINST FGF23: FINAL RESULTS OF A PHASE 3 TRIAL M. L. Brandi, A. A. Portale, T. O. Carpenter, K. Briot, E. A. Imel, P. Kamenický, T. J. Weber, P. Pitukcheewanont, H. I. Cheong, S. Jan de Beur, Y. Imanishi, N. Ito, R. Lachmann, H. Tanaka, F. Perwad, L. Zhang, A. Skrinar, L. Rees, K. L. Insogna
OP2 - P1133 DOES ENDOGENOUS INFLAMMATION EXPLAIN ETHNIC VARIATION IN BONE MINERAL DENSITY? RESULTS FROM THE SABRE COHORT STUDY R. Durdin, C. Parsons, E. M. Dennison, S. Williams, T. Tillin, N. Chaturvedi, C. Cooper, N. C. Harvey, K. Ward
OP3 - P581 AN INTERACTIVE BENEFITS AND BUDGET IMPACT CALCULATOR TO ESTIMATE POTENTIAL EFFECTS OF FRACTURE LIAISON SERVICES R. Pinedo-Villanueva, A. Sami, S. Kolovos, E. Burn, M. Fujita, P. Halbout, C. Cooper, M. K. Javaid
OP4 - P236 PHASE I/III STUDY TO CONFIRM BIOEQUIVALENCE AND SAFE SWITCHING OF PROPOSED BIOSIMILAR DENOSUMAB IN POSTMENOPAUSAL OSTEOPOROSIS J.-J. Body, C. Nie, B. Vogg, R. Eastell
OP5 - P255 SARCOPENIA AND HEALTH-RELATED OUTCOMES: AN UMBRELLA REVIEW OF OBSERVATIONAL STUDIES N. Veronese, J. Demurtas, P. Soysal, L. Smith, O. Bruyere, J.-Y. Reginster, C. Beaudart, C. Cooper, M. Mirko, S. Maggi
OP6 - P463 HORMONE THERAPY REDUCES THE RISK OF FRACTURE REGARDLESS OF BASELINE FRACTURE RISK – RESULTS FROM THE WOMEN’S HEALTH INITIATIVE HORMONE THERAPY TRIALS M. Lorentzon, H. Johansson, N. Harvey, E. Liu, C. Crandall, E. McCloskey, J. Kanis
OP7 - P559 DISABILITY-ADJUSTED LIFE YEARS RELATED TO FRAGILITY FRACTURES F. Borgström, N. V. Norton, L. Karlsson, G. Ortsäter, N. C. Harvey, E. V. McCloskey, J. A. Kanis
OP8 - P1265 INTEGRATED SAFETY SUMMARY OF THE NOVEL, INTRA-ARTICULAR AGENT LORECIVIVINT (LOR; SM04690), A CLK/DYRK1A INHIBITOR THAT MODULATES THE WNT PATHWAY, IN SUBJECTS WITH KNEE OSTEOARTHRITIS I. Simsek, C. Swearingen, S. Kennedy, J. Tambiah, C. Damatarca, Y. Yazici, N. Lane, M. Hochberg
OP9 - P590 INTRA-ARTICULAR CORTICOSTEROID KNEE INJECTION INDUCES A REDUCTION IN MENISCAL THICKNESS WITH NO TREATMENT EFFECT ON CARTILAGE VOLUME: A CASE-CONTROL STUDY J.-P. Pelletier, J.-P. Raynauld, F. Abram, M. Dorais, P. Paiement, J. Martel-Pelletier
OP10 - P876 ASSOCIATION BETWEEN SARC-F AND QUALITY OF LIFE MEASURED WITH THE SARQOL® QUESTIONNAIRE IN OLDER, COMMUNITY-DWELLING SUBJECTS FROM THE SARCOPHAGE COHORT A. Geerinck, C. Beaudart, M. Locquet, J.-Y. Reginster, O. Bruyère
OP11 - P438 FEASIBILITY, SAFETY AND EFFECTIVENESS OF A 16-WEEK HOME-BASED HOPPING AND JUMPING PILOT EXERCISE INTERVENTION IN POST-MENOPAUSAL WOMEN WITH LOW BONE MINERAL DENSITY C.-A. Ng, L. B. McMillan, J. Mesinovic, L. Humbert, P. R. Ebeling, D. Scott
OP12 - P579 BONE DENSITOMETRY WORLDWIDE: A GLOBAL SURVEY BY THE ISCD AND IOF M. A. Clynes, L.D. Westbury, E. M. Dennison, J. A. Kanis, M. K. Javaid, N. C. Harvey, M. Fujita, C. Cooper, W. D. Leslie, C. R. Shuhart
OP13 - P1104 EPIGENOME-WIDE ASSOCIATION STUDY IDENTIFIES ASSOCIATION BETWEEN 5’ WNT5B CPG DNA METHYLATION AND BONE MINERAL DENSITY AT THE FEMORAL NECK IN OLDER UK ADULTS N. R. Fuggle, E. M. Dennison, C. G. Bell, C. Cooper
OP14 - P687 IDENTIFICATION OF FRAIL PATIENTS USING FEMORAL RADIOFREQUENCY ECHOGRAPHIC MULTI SPECTROMETRY (REMS) G. Adami, G. Arioli, G. Bianchi, M. L. Brandi, C. Caffarelli, L. Cianferotti, G. Girasole, S. Gonnelli, M. Manfredini, M. Muratore, E. Quarta, L. Quarta, D. Gatti
OP15 - P954 FRACTURE RISK SCREENING USING FRAX IS EFFECTIVE FOR SECONDARY FRACTURE PREVENTION: A POST-HOC ANALYSIS OF THE SCOOP TRIAL C. Parsons, E. M. Curtis, L. Shepstone, J. A. Kanis, E. Lenaghan, S. Clarke, R. Fordham, N. Gittoes, I. Harvey, R. The Netherlands, N. M. Redmond, A. Howe, T. Marshall, T. J. Peters, D. Torgerson, T. W. O’Neil, E. McCloskey, N. C. Harvey, C. Cooper
OP16 - P874 EVALUATING QUALITY OF LIFE IN FRAILTY: APPLICABILITY AND PSYCHOMETRIC PROPERTIES OF THE SARQOL® QUESTIONNAIRE A. Geerinck, M. Locquet, O. Bruyère, J.-Y. Reginster, C. Beaudart
OP17 - P1019 HEALTH SERVICE USE AND RECOVERY OF QUALITY OF LIFE 12-MONTHS POST-FRACTURE: LATENT CLASS ANALYSES OF THE INTERNATIONAL COST AND UTILITIES RELATED TO OSTEOPOROTIC FRACTURES STUDY (ICUROS) J. Talevski, K. Sanders, L. Busija, C. Connaughton, A. Beauchamp, G. Duque, K. Lim, F. Borgström, J. A. Kanis, S. Brennan-Olsen
OP18 - P1293 COMPARATIVE FUNCTIONAL STATUS BETWEEN CENTENARIES AND OLDER ADULTS WITH HIP FRACTURE IN SPAIN: DATA FORM THE SPANISH NATIONAL HIP FRACTURE REGISTRY (RNFC) B. A. Cedeno-Veloz, M. Gonzalo Lazaro, C. Bermejo Boixareu, A. Guijarro Valtuena , L. Navarro Castellanos, P. Saez-Lopez, R. Queipo, C. Ojeda-Thies, P. Gomez Campelo, J. I. Gonzalez Montalvo
OP19 - P880 SARCOPENIA ACCORDING TO EWGSOP2 IS ASSOCIATED WITH GLOBAL SAGITTAL IMBALANCE OF THE SPINE IN OLDER ADULTS: THE SAFE COHORT STUDY M. Hars, A. Faundez, J. Fechtenbaum, K. Briot, C. Roux, F. Herrmann, S. Ferrari, S. Genevay, S. Boudabbous, A. Trombetti
OP20 - P875 DEVELOPMENT OF A SHORT VERSION OF THE SARCOPENIA QUALITY OF LIFE (SARQOL®) QUESTIONNAIRE A. Geerinck, O. Bruyère, M. Locquet, S. Gillain, C. Monseur, J.-Y. Reginster, C. Beaudart
LONG-TERM SAFETY IN ADULTS WITH X-LINKED HYPOPHOSPHATEMIA (XLH) TREATED WITH BUROSUMAB, A FULLY HUMAN MONOCLONAL ANTIBODY AGAINST FGF23: FINAL RESULTS OF A PHASE 3 TRIAL
M. L. Brandi, A. A. Portale, T. O. Carpenter, K. Briot, E. A. Imel, P. Kamenický, T. J. Weber, P. Pitukcheewanont, H. I. Cheong, S. Jan de Beur, Y. Imanishi, N. Ito, R. Lachmann, H. Tanaka, F. Perwad, L. Zhang, A. Skrinar, L. Rees, K. L. Insogna
OP2 - P1133
DOES ENDOGENOUS INFLAMMATION EXPLAIN ETHNIC VARIATION IN BONE MINERAL DENSITY? RESULTS FROM THE SABRE COHORT STUDY
R. Durdin, C. Parsons, E. M. Dennison, S. Williams, T. Tillin, N. Chaturvedi, C. Cooper, N. C. Harvey, K. Ward
OP3 - P581
AN INTERACTIVE BENEFITS AND BUDGET IMPACT CALCULATOR TO ESTIMATE POTENTIAL EFFECTS OF FRACTURE LIAISON SERVICES
R. Pinedo-Villanueva, A. Sami, S. Kolovos, E. Burn, M. Fujita, P. Halbout, C. Cooper, M. K. Javaid
OP4 - P236
PHASE I/III STUDY TO CONFIRM BIOEQUIVALENCE AND SAFE SWITCHING OF PROPOSED BIOSIMILAR DENOSUMAB IN POSTMENOPAUSAL OSTEOPOROSIS
J.-J. Body, C. Nie, B. Vogg, R. Eastell
OP5 - P255
SARCOPENIA AND HEALTH-RELATED OUTCOMES: AN UMBRELLA REVIEW OF OBSERVATIONAL STUDIES
N. Veronese, J. Demurtas, P. Soysal, L. Smith, O. Bruyere, J.-Y. Reginster, C. Beaudart, C. Cooper, M. Mirko, S. Maggi
OP6 - P463
HORMONE THERAPY REDUCES THE RISK OF FRACTURE REGARDLESS OF BASELINE FRACTURE RISK – RESULTS FROM THE WOMEN’S HEALTH INITIATIVE HORMONE THERAPY TRIALS
M. Lorentzon, H. Johansson, N. Harvey, E. Liu, C. Crandall, E. McCloskey, J. Kanis
OP7 - P559
DISABILITY-ADJUSTED LIFE YEARS RELATED TO FRAGILITY FRACTURES
F. Borgström, N. V. Norton, L. Karlsson, G. Ortsäter, N. C. Harvey, E. V. McCloskey, J. A. Kanis
OP8 - P1265
INTEGRATED SAFETY SUMMARY OF THE NOVEL, INTRA-ARTICULAR AGENT LORECIVIVINT (LOR; SM04690), A CLK/DYRK1A INHIBITOR THAT MODULATES THE WNT PATHWAY, IN SUBJECTS WITH KNEE OSTEOARTHRITIS
I. Simsek, C. Swearingen, S. Kennedy, J. Tambiah, C. Damatarca, Y. Yazici, N. Lane, M. Hochberg
OP9 - P590
INTRA-ARTICULAR CORTICOSTEROID KNEE INJECTION INDUCES A REDUCTION IN MENISCAL THICKNESS WITH NO TREATMENT EFFECT ON CARTILAGE VOLUME: A CASE-CONTROL STUDY
J.-P. Pelletier, J.-P. Raynauld, F. Abram, M. Dorais, P. Paiement, J. Martel-Pelletier
OP10 - P876
ASSOCIATION BETWEEN SARC-F AND QUALITY OF LIFE MEASURED WITH THE SARQOL® QUESTIONNAIRE IN OLDER, COMMUNITY-DWELLING SUBJECTS FROM THE SARCOPHAGE COHORT
A. Geerinck, C. Beaudart, M. Locquet, J.-Y. Reginster, O. Bruyère
OP11 - P438
FEASIBILITY, SAFETY AND EFFECTIVENESS OF A 16-WEEK HOME-BASED HOPPING AND JUMPING PILOT EXERCISE INTERVENTION IN POST-MENOPAUSAL WOMEN WITH LOW BONE MINERAL DENSITY
C.-A. Ng, L. B. McMillan, J. Mesinovic, L. Humbert, P. R. Ebeling, D. Scott
OP12 - P579
BONE DENSITOMETRY WORLDWIDE: A GLOBAL SURVEY BY THE ISCD AND IOF
M. A. Clynes, L.D. Westbury, E. M. Dennison, J. A. Kanis, M. K. Javaid, N. C. Harvey, M. Fujita, C. Cooper, W. D. Leslie, C. R. Shuhart
OP13 - P1104
EPIGENOME-WIDE ASSOCIATION STUDY IDENTIFIES ASSOCIATION BETWEEN 5’ WNT5B CPG DNA METHYLATION AND BONE MINERAL DENSITY AT THE FEMORAL NECK IN OLDER UK ADULTS
N. R. Fuggle, E. M. Dennison, C. G. Bell, C. Cooper
OP14 - P687
IDENTIFICATION OF FRAIL PATIENTS USING FEMORAL RADIOFREQUENCY ECHOGRAPHIC MULTI SPECTROMETRY (REMS)
G. Adami, G. Arioli, G. Bianchi, M. L. Brandi, C. Caffarelli, L. Cianferotti, G. Girasole, S. Gonnelli, M. Manfredini, M. Muratore, E. Quarta, L. Quarta, D. Gatti
OP15 - P954
FRACTURE RISK SCREENING USING FRAX IS EFFECTIVE FOR SECONDARY FRACTURE PREVENTION: A POST-HOC ANALYSIS OF THE SCOOP TRIAL
C. Parsons, E. M. Curtis, L. Shepstone, J. A. Kanis, E. Lenaghan, S. Clarke, R. Fordham, N. Gittoes, I. Harvey, R. The Netherlands, N. M. Redmond, A. Howe, T. Marshall, T. J. Peters, D. Torgerson, T. W. O’Neil, E. McCloskey, N. C. Harvey, C. Cooper
OP16 - P874
EVALUATING QUALITY OF LIFE IN FRAILTY: APPLICABILITY AND PSYCHOMETRIC PROPERTIES OF THE SARQOL® QUESTIONNAIRE
A. Geerinck, M. Locquet, O. Bruyère, J.-Y. Reginster, C. Beaudart
OP17 - P1019
HEALTH SERVICE USE AND RECOVERY OF QUALITY OF LIFE 12-MONTHS POST-FRACTURE: LATENT CLASS ANALYSES OF THE INTERNATIONAL COST AND UTILITIES RELATED TO OSTEOPOROTIC FRACTURES STUDY (ICUROS)
J. Talevski, K. Sanders, L. Busija, C. Connaughton, A. Beauchamp, G. Duque, K. Lim, F. Borgström, J. A. Kanis, S. Brennan-Olsen
OP18 - P1293
COMPARATIVE FUNCTIONAL STATUS BETWEEN CENTENARIES AND OLDER ADULTS WITH HIP FRACTURE IN SPAIN: DATA FORM THE SPANISH NATIONAL HIP FRACTURE REGISTRY (RNFC)
B. A. Cedeno-Veloz, M. Gonzalo Lazaro, C. Bermejo Boixareu, A. Guijarro Valtuena , L. Navarro Castellanos, P. Saez-Lopez, R. Queipo, C. Ojeda-Thies, P. Gomez Campelo, J. I. Gonzalez Montalvo
OP19 - P880
SARCOPENIA ACCORDING TO EWGSOP2 IS ASSOCIATED WITH GLOBAL SAGITTAL IMBALANCE OF THE SPINE IN OLDER ADULTS: THE SAFE COHORT STUDY
M. Hars, A. Faundez, J. Fechtenbaum, K. Briot, C. Roux, F. Herrmann, S. Ferrari, S. Genevay, S. Boudabbous, A. Trombetti
OP20 - P875
DEVELOPMENT OF A SHORT VERSION OF THE SARCOPENIA QUALITY OF LIFE (SARQOL®) QUESTIONNAIRE
A. Geerinck, O. Bruyère, M. Locquet, S. Gillain, C. Monseur, J.-Y. Reginster, C. Beaudart